UNRAVELLING ANTIGENIC CROSS-REACTIONS TOWARD THE WORLD OF CORONAVIRUSES: EXTENT OF THE STABILITY OF SHARED EPITOPES AND SARS-COV-2 ANTI-SPIKE CROSS-NEUTRALIZING ANTIBODIES

The human immune repertoire retains the molecular memory of a very great diversity of target antigens (epitopes) and can recall this upon a second encounter with epitopes against which it has previously been primed.Although genetically diverse, proteins of coronaviruses exhibit sufficient conservation to lead to antigenic cross-reactions.In this re

Airway epithelial cells, which lines the respiratory mucosa is in direct contact with the environment.Airway epithelial cells are the primary target for rhinovirus and other inhaled pathogens.In response to rhinovirus infection, airway epithelial cells mount both pro-inflammatory responses and antiviral innate immune responses to Cord clear the vir

Design solutions of domestic VLSI were obtained as a result of the application of computeraided design tools of a foreign supplier (CAD Synopsys, Cadence Design Systems and Mentor Graphics), based on standard libraries of PDK elements (Project Design KIT) of factories and IC-modules also supplied mainly by foreign companies.As a rule, the developer

Study on large-scale electrochemical energy storage simulation is carried out in Camera Grip this paper to discuss its feasibility in enhancing the stability of HVDC power transmission, thus providing a reference for large-scale energy storage planning and design in the background of global energy internet.The paper introduces the development statu